Resolved Drug Shortages: Amino Acid Injection

Drug NameCompanyInformationRelated InformationAcyclovir Tablets and Capsules    7/2/2010Teva Pharmaceuticals
1-800-545-8800 GlaxoSmithKline
Mylan Pharmaceuticals
1-800-796-9526       Carlsbad Technologies, Inc.
1-760-431-8284Teva is releasing acyclovir tablets as they become available. GlaxoSmithKline has Zovirax 200mg, 400mg, and 800 mg tablets available.
   Mylan reports the following available presentations:
Acyclovir Capsules USP, 200 mg, Bottles of 100, NDC 0378-2200-01
Acyclovir Capsules USP, 200 mg, Bottles of 500, NDC 0378-2200-05
Acyclovir Tablets USP, 400 mg, Bottles of 100, NDC 0378-0253-01
Acyclovir Tablets USP, 400 mg, Bottles of 500, NDC 0378-0253-05
Acyclovir Tablets USP, 800 mg, Bottles of 100 NDC 0378-0302-01
Acyclovir Tablets USP, 800 mg, Bottles of 500, NDC 0378-0302-05  Carlsbad is releasing acyclovir tablets as they become available. 
Amino Acid Injection9/19/2011Hospira Customer Service
1-877-946-7747Baxter Customer Service:
1-888-229-0001B Braun Customer Service
1-800-227-2862No further supply issues anticipated.
Aminophylline injection2/1/2011
1-877-946-7747Hospira has aminophylline 25 mg/mL 10 mL vials (NDC 00409-5921-01) and 20 mL vials (NDC 00409-5922-01).
Arginine 10% injection (R-Gene 10)8/15/2011Pfizer Customer Service
1-866-485-1359Pfizer has R-Gene 10 injection (NDC 00009-0436-24) available.
Atracurium injection12/17/2010
Customer service
1-800-562-4797No further supply issues anticipated.
Aztreonam for Injection 7/1/2010 BMS
1-800-332-2056  Baxter
1-888-229-0001 APP
1-888-386-1300      Baxter has frozen aztreonam 1 gram (NDC 00003-2230-11) and 2 gram (NDC 00003-2240-11) presentations. Aztreonam for Injection, USP is now available from APP in the following presentations:
1gm vial 63323-401-20
2gm vial 63323-402-20The product is now available through wholesalers or APP.
BICNU (Carmustine) Injection, 100 mg (NDC 00015-3012-60)5/23/2011 Bristol-Myers Squibb is now releasing BICNU injection.Bumetanide Injection5/11/2011Hospira
1-800-562-4797No further supply issues anticipated.
Calcium Disodium Versenate Injection 200 mg/mL 5 mL ampules (NDC 29336-400-10)




Graceway Pharmaceuticals,
1-484-321-5600Product is now available with a new NDC #29336-400-10.

Cerezyme (imiglucerase) Injection


Genzyme Corporation

For inquiries contact Genzyme Medical Information: This e-mail address is being protected from spambots. You need JavaScript enabled to view it or 1-800-745-4447, option 2Dear Healthcare Provider Letter (PDF - 338KB)Cleviprex 0.5 mg/mL 50 mL vial (NDC 65293-0002-50) 100 mL vial (NDC 65293-0002-00)9/8/2011The Medicines CompanyThe Medicines Company has Cleviprex 0.5mg/ml 50 ml vials (NDC 65293-0002-50) available by drop shipment through wholesalers.  The 100ml vials do not yet have an availability date.DDAVP Nasal Solution 0.01% Rhinal Tube9/1/2010
1-800-981-2491The product is again available.
Dexrazoxane for Injection, Zinecard



Pfizer- Zinecard:

Ben Venue- Dexrazoxane (generic):

Zinecard now available from Pfizer. See Dear Health Care Provider Letter (PDF - 39KB)


Totect available, labeled for use in treatment of extravasation resulting from IV anthracycline chemotherapy. TopoTarget inquiries:


Dexrazoxane (generic)- product remains unavailable from Ben Venue due to manufacturing delays

Dextrose 50% injection12/22/2010
 Hospira Inc.
Amphastar Pharmaceuticals, Inc./IMS
1-800-423-4136Hospira has 50% dextrose injection in 50 mL Lifeshield syringes (NDC 00409-4902-34), 50 mL Ansyr II luer-lock syringes (NDC 00409-7517-16), and 50 mL vials (NDC 00409-6648-02). Amphastar (IMS) has dextrose 50% Luer-Jet syringes (NDC 00548-3301-00) available



Lundbeck has released new production.

Ephedrine Injection




Sandoz (formerly Parenta)


Akorn Pharmaceuticals

All 3 firms report ongoing releases.

Hospira Inc.,


Amphastar Pharmaceuticals, Inc./IMS

Hospira has epinephrine 0.1 mg/mL Lifeshield Abboject emergency syringes (NDC 00409-4921-34) and 0.1 mg/mL Abboject intracardiac emergency syringes (NDC 00409-4901-18).

Amphastar (IMS) has epinephrine 0.1 mg/mL 10 mL syringes (NDC 00548-3316-00).

(epoetin alfa)12/22/2010
 Procrit - Centocor Ortho Biotech, Inc.
(1-800-547-6446) Epogen - Amgen, Inc.
(1-800-772-6436)Centocor Ortho Biotech recalled multiple Procrit lots but reports unaffected product available for all Procrit presentations.Amgen recalled multiple Epogen (epoetin alfa) lots but reports unaffected product available for all presentations.
Erythromycin lactobionate injection6/24/2011Hospira Inc.
1-877-946-7747Both presentations: ample levels of inventory to support market demand.
Erythromycin Ophthalmic Ointment



Bausch and Lomb Customer Service Number



Fera Pharmaceutical, LLC
(414) 434-6604

Bausch & Lomb is currently releasing erythromycin ophthalmic ointment as it becomes available.


Fera Pharmaceuticals has available Erythromycin Ophthalmic Ointment USP, 1g x 50, NDC#48102-008-11, 3.5 g tube in 24 count cartons as well as the single 3.5 g tube.

Fentanyl Transdermal System6/23/2011Ortho-McNeil Janssen
Customer Service:
1-800-526-7736Apotex Corporation Customer Service:
1-(877)-4-ApotexSandoz Customer Service:
1-609-627-8500Mylan Customer Service:
1-800-796-9526Watson Customer Service:
724-514-1800 or 800-272-5525Actavis Customer Service:
800-432-8534 or fax (973) 993-4300 or E-mail:
This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Mallinckrodt Inc.
(800) 325-8888

All product available.Foradil Aerolizer3/3/2011
 MerckForadil Aerolizer is available to address the shortage.  Merck is temporarily  supplying Foradil with the older version of the MedGuide - Please see the
Dear Pharmacist Letter (PDF - 44KB).

New production is anticipated to be available in March 2011 with the new MedGuide and no further shortages are anticipated.

Gemfibrozil Tablets







Camber Pharmaceuticals
1- 866-495-1995



Teva Pharmaceuticals

Pfizer has available Lopid 600 mg tablets in 60 (NDC 00071-0737-20) and 500 (NDC 00071-0737-30) count presentations.



Camber has gemfibrozil available in 60 count (NDC 31722-0225-60) and 500 count (NDC 31722-0225-05) sizes.



Teva has gemfibrozil 600 mg tablets in 60 count and 500 count presentations on allocation.

 Eli Lilly
1-800-545-5979Novo Nordisk
1-800-562-4797 All 3 firms report availability.
Heparin Sodium Large Volume Premixed Infusion Solutions9/24/2010
 B. Braun
1-800- 227-2862Baxter
 Hospira and B. Braun report availability.
Indomethacin for injection




Bedford Customer Service




Lundbeck Inc. Customer Service

Bedford now has Indomethacin injection in 1mg vials available (NDC 55390-299-01) and this product is being released to wholesalers.



Indocin IV is currently not available from Lundbeck.

Intron A (interferon alfa-2b, recombinant) for Injection



Customer Service Number:
1-800-222-7579Merck has the INTRON A Powder for Injection and Solution for Injection in Vials in good supply.

Isoniazid Injection (NDC 00781-3056-70)



Sandoz (customer service number)

Product continues to be available with short expiration dating.Levorphanol 2mg Tablets8/26/2011Roxane Laboratories
1-614-276-4000Levorphanol 2mg tablets are now available.
Methotrexate injection



Bedford Laboratories Customer Service


Bioniche Pharma


Ebewe Parenta Pharmaceuticals, Inc.


Hospira Customer Service


APP Pharmaceuticals Customer Service

Methotrexate injection is available in multiple presentations and no further shortages are anticipated. For specific information regarding available strengths/sizes, please contact the manufacturers.

Ben Venue (Bedford)
Customer service:

Accord Healthcare Inc.

Bedford reports all mitomycin presentations are available.

Accord has mitomycin 20 mg vials (NDC 16729-0108-11) and 5 mg vials (NDC 16729-0115-05).

Morphine Injection (2 mg, 4 mg, 8 mg, and 10 mg)





No further supply issues anticipated.

Morphine Sulfate Oral Solution

100mg per 5ml (20mg/ml), 20mg/5ml and 10mg/5ml


Roxane Laboratories
Customer Service (1-800 520-1631)








Roxane Laboratories has recently received FDA approval for Morphine Sulfate Oral solution 100mg per 5ml (20 mg/ml). This is the only FDA approved morphine sulfate oral solution available at this concentration. The firm has sufficient supply to meet the entire market demand and no shortage is anticipated.

Morphine 20mg/5ml and 10mg/5ml remain available as approved products as well.

For the morphine 100mg per 5ml (20mg/ml), there will be a transition period to the new packaging, labeling, and NDC numbers. In the meantime, please continue to use the following NDC numbers:

NDC 0054-0352-44 Morphine Sulfate Oral Solution CII, 20mg/mL 30mL Bottle.

NDC 0054-0352-50 Morphine Sulfate Oral Solution CII, 20mg/mL 120mL Bottle.

Naloxone Injection




Hospira and Amphastar-IMS report availability and no further supply issues are anticipated.

Nimbex (cisatracurium) injection



Abbott Laboratories
1-800-255-5162Abbott reports availability of all presentations.Nitroglycerin in Dextrose 5%


Baxter Customer Service:
Hospira Inc.

The product is now available.Nitroglycerin Solution 5mg/ml 10ml (NDC 00517-4810-253/18/2011
631-924-4000Luitpold now has product available.
Nitrostat sublingual tablets (0.3 mg, 0.4 mg, and 0.6 mg) updated
4/13/2010Pfizer Inc.Pfizer has sufficient inventory and is able to meet market demand. Dear Healthcare Provider Letter (PDF - 451KB)Octreoscan (Kit for the Preparation of Indium In 111 Pentetreotide) 2/12/2010Covidien Product Monitoring and Drug Safety
1-800-778-7898Please see Dear Valued Customer Letter (PDF - 25KB)Pancuronium Injection2/1/2011
1-877-946-7747Hospira has pancuronium injection 1 mg/mL in 10 mL vials (NDC 00409-4646-01) available.
Pentosan Polysulfate sodium 100mg capsules
NDC 50458-098-017/18/2011Ortho Woman’s Health & Urology
 No further supply issues anticipated.
Photofrin (porfimer sodium) Injection10/13/2010
Customer Service:
1-888-738-1411Photofrin is now available again and no further shortage is anticipated.
Pre-pen (benzyl penicilloyl-polylysine) injection 12/08/2009Pre-Pen is being manufactured by Allerquest and distributed by ALK-Abello (1-800-325-7354)Pre-Pen has been reintroduced to the market and is now available.Regonol injection, 5 mg/mL, 2 mL ampules (NDC 00781-3040-95)3/25/2011
 Sandoz has begun shipping again and is no longer on backorder.
Renacidin Irrigation
NDC 00327-0011-055/23/2011Manufacturing delaysGuardian Laboratories now has Renacidin available.
Sinemet (carbidopa-levodopa) 25 mg/100 mg tablets2/22/2011 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. Contact: Merck National Service Center:
 Merck has changed its manufacturing supply source of Sinemet and Sinemet CR and is releasing product.
Succinylcholine injection7/19/2011Sandoz
1-877-946-7747No further supply issues anticipated.
Tamiflu for Oral Suspension8/24/2011Genentech
1-800-551-2231Genentech has available a new Tamiflu 6 mg/mL oral suspension in 100 mL bottles (NDC 00004-0820-09). Tamiflu 12 mg/mL suspension has been discontinued.
Technetium Tc99m Generators12/21/2010
(Ultra-Technekow DTE, NDA 17-243)
(Technelite, NDA 17-771)Adequate supply is now available.
Thyroid (desiccated) tablets6/24/2011Forest RLCFDA approved levothyroxine products continue to be available from multiple manufacturers.Tikosyn (500mcg and 250mcg capsules) 1/15/2010Pfizer Inc.Please see Dear Healthcare Professional Letter (PDF - 29KB) for additional information Trecator (ethionamide) 250mg tablets NDC 00008-4117-013/25/2011 Wyeth
 Pharmacies may obtain this product by contacting their wholesaler to place a drop shipment order. Routine wholesaler shipments are expected to resume by late April 2011. For any problems obtaining Trecator through this process, Wyeth may be contacted at 1-800-666-7248.
Tromethamine6/24/2011Hospira Inc. Customer Service:
1-877-946-7747Product 500 mL (NDC 0409-1593-04):  ample levels of inventory to support market demand.
Xeloda 500 Tablets8/3/2011Genentech
1-800-GENENTECHGenentech has released new production.

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